Determinants of participation in prostate cancer screening: A simple analytical framework to account for healthy-user bias
نویسندگان
چکیده
In Japan at present, fecal occult blood testing (FOBT) is recommended for cancer screening while routine population-based prostate-specific antigen (PSA) screening is not. In future it may be necessary to increase participation in the former and decrease it in the latter. Our objectives were to explore determinants of PSA-screening participation while simultaneously taking into account factors associated with FOBT. Data were gathered from a cross-sectional study conducted with random sampling of 6191 adults in Osaka city in 2011. Of 3244 subjects (return rate 52.4%), 936 men aged 40-64 years were analyzed using log-binomial regression to explore factors related to PSA-screening participation within 1 year. Only responders for cancer screening, defined as men who participated in either FOBT or PSA-testing, were used as main study subjects. Men who were older (prevalence ratio [PR] [95% confidence interval (CI)] = 2.17 [1.43, 3.28] for 60-64 years compared with 40-49 years), had technical or junior college education (PR [95% CI] = 1.76 [1.19, 2.59] compared with men with high school or less) and followed doctors' recommendations (PR [95% CI] = 1.50 [1.00, 2.26]) were significantly more likely to have PSA-screening after multiple variable adjustment among cancer-screening responders. Attenuation in PR of hypothesized common factors was observed among cancer-screening responders compared with the usual approach (among total subjects). Using the analytical framework to account for healthy-user bias, we found three factors related to participation in PSA-screening with attenuated association of common factors. This approach may provide a more sophisticated interpretation of participation in various screenings with different levels of recommendation.
منابع مشابه
Re: Determinants of participation in prostate cancer screening: A simple analytical framework to account for healthy-user bias
D ear Editor, Recently, Tabuchi et al. (Cancer Sci 2015; 106: 108– 14) investigated “determinants of prostate-specific antigen (PSA)-based screening participation while simultaneously taking into account factors associated with fecal occult blood test (FOBT).” They found “three factors related to healthy-user bias: i.e., older age, a technical or junior college education, and adherence to docto...
متن کاملAssessing the Diagnostic Value of Plasma-Free DNA in Prostate Cancer Screening
Background: Prostate cancer is the second form of cancer among men worldwide. For early cancer detection, we should identify tumors in initial stages before the physical signs become visible. The present study aims to evaluate the diagnostic value of cell-free DNA (cfDNA), its comparison with prostate-specific antigen (PSA) level in prostate cancer screening and also in patients with localized ...
متن کاملPredictors of Common Cancer Screening Behavior in Middle-Aged Iranian Men Working at University Using the Health Belief Model
Background: Men are more likely than women to have cancer and die from it. In addition, the likelihood of using healthcare services and preventive measures, such as screening for cancer, is much lower among men than women. This study aimed to determine the predictors of cancer screening behavior in middle-aged men employed in universities using the Health Belief Model. Materials and Methods: Th...
متن کاملHealth Literacy and Men\'s Attitudes and Practices toward Prostate Cancer Screening
Background: Health literacy as a vital indicator of health care costs plays an important role in facilitating effective health communication strategies. Screening is one of these strategies, so that intervention and management can be provided ahead of schedule. The aim of this study was to determine the relationship between health literacy and men's practices and their attitude toward prosta...
متن کاملPSA Screening in Prostate Cancer
Introduction: Prostate cancer is one of the most common cancers in Iranian men. PSA(prostate specific antigen) screening is a controversial issue because PSA screening leads to diagnose of patients with low risk prostate cancer who not only do not benefit from treatment but also suffer from complication caused by treatment. On the other hand, without prostate cancer screening, the rate of meta...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 106 شماره
صفحات -
تاریخ انتشار 2015